

Research Team
Daniel M. Mackin, PhD
Daniel M. Mackin, PhD
Postdoctoral Fellow, Artificial Intelligence and Mental Health: Innovation in Technology Guided Healthcare Lab at Dartmouth, Center for Technology and Behavioral Health, Geisel School of Medicine at Dartmouth
Dr. Daniel M. Mackin is a postdoctoral fellow in Biomedical Data Science working with Dr. Nicholas C. Jacobson in his AI and Mental Health: Innovation in Technology Guided Healthcare (AIM HIGH) Lab in Dartmouth College’s Center for Technology and Behavioral Health. He received his PhD in Clinical Psychology from Stony Brook University and completed his clinical fellowship at the Warren Alpert Medical School of Brown University.
Dr. Mackin is interested in integrating multiple levels of analysis to study the development and course of internalizing psychopathology. He is also interested in improving assessment and classification of these disorders. Dr. Mackin’s program of research has examined how reward processing, reinforcement learning, life stress, and personality influence depressive and anxiety disorders longitudinally. He has also developed measures assessing subtypes of Major Depressive Disorder. During his fellowship, Dan is working to apply machine learning techniques to passive sensor data from smartphone and wearable devices to better assess and predict real-time fluctuations in depressive symptoms. He is also interested in developing and implementing personalized just-in-time adaptive interventions (JITAIs).
In his free time, Dr. Mackin enjoys golfing, kayaking, hiking, reading and spending time with his family and dog.
Selected Publications
- Mackin DM, Goldstein BL, Mumper E, Kujawa A, Kessel EM, Olino TM, Nelson BD, Hajcak G, Klein DN. Longitudinal associations between reward responsiveness and depression across adolescence. J Am Acad Child Adolesc Psychiatry. 2023 Jul;62(7):816-828. doi: 10.1016/j.jaac.2022.11.013. PMID: 36764607; PMCID: PMC10313752.
- Zimmerman M, Mackin DM. Reliability and validity of the difficult to treat depression questionnaire (DTDQ). Psychiatry Res. 2023 Jun;324:115225. doi: 10.1016/j.psychres.2023.115225. PMID: 37116322.
- Zimmerman M, Thompson JS, Mackin DM. The relative importance of diagnostic specific and transdiagnostic factors in evaluating treatment outcome of depressed patients. Psychiatry Res. 2022 Nov;317:114883. doi: 10.1016/j.psychres.2022.114883. PMID: 36240633.
- Hyland S, Mackin DM, Goldstein BL, Finsaas MC, Klein DN. Agreement, stability, and validity of parent- and youth-reported anxiety symptoms from childhood to adolescence. Res Child Adolesc Psychopathol. 2022 Nov;50(11):1445-1455. doi: 10.1007/s10802-022-00941-1. PMID: 35652991; PMCID: PMC10071959.
- Mackin DM, Finsaas MC, Nelson BD, Perlman G, Kotov R, Klein DN. Intergenerational transmission of depressive and anxiety disorders: Mediation via youth personality. J Psychopathol Clin Sci. 2022 Jul;131(5):467-478. doi: 10.1037/abn0000759. PMID: 35653755; PMCID: PMC9292465.
- Goldstein BL, Mackin DM, Miao J, Perlman G, Watson D, Ormel J, Klein DN, Kotov R. Is personality stable and symptoms fleeting? A longitudinal comparison in adolescence. J Res Pers. 2022 Apr;97:104190. doi: 10.1016/j.jrp.2022.104190. PMID: 35241862; PMCID: PMC8887882.
- Michelini G, Perlman G, Tian Y, Mackin DM, Nelson BD, Klein DN, Kotov R. Multiple domains of risk factors for first onset of depression in adolescent girls. J Affect Disord. 2021 Mar 15;283:20-29. doi: 10.1016/j.jad.2021.01.036. PMID: 33516083; PMCID: PMC7954924.
- Mahaffey BL, Mackin DM, Rosen J, Schwartz RM, Taioli E, Gonzalez A. The disaster worker resiliency training program: a randomized clinical trial. Int Arch Occup Environ Health. 2021 Jan;94(1):9-21. doi: 10.1007/s00420-020-01552-3. PMID: 32448931; PMCID: PMC7245643.
- Mackin DM, Nelson BD, Klein DN. Reward processing and depression: Current findings and future directions. In Martin CR, Hunter LA, Preedy VR, Patel V, Rajendram R, editors. The Neuroscience of Depression: Genetics, Cell Biology, Neurology, Behaviour and Diet. Kings College, London: Elsevier. 2021. pp.425-433.
- Mahaffey BL, Mackin DM, Vranceanu AM, Lofaro L, Bromet EJ, Luft BJ, Gonzalez A. The Stony Brook Health Enhancement Program: The development of an active control condition for mind-body interventions. J Health Psychol. 2020 Nov-Dec;25(13-14):2129-2140. doi: 10.1177/1359105318787024. PMID: 30010422; PMCID: PMC8331223.
- Mackin DM, Kotov R, Perlman G, Nelson BD, Goldstein BL, Hajcak G, Klein DN. Reward processing and future life stress: Stress generation pathway to depression. J Abnorm Psychol. 2019 May;128(4):305-314. doi: 10.1037/abn0000427. Erratum in: J Abnorm Psychol. 2019 Aug;128(6):492. PMID: 31045413; PMCID: PMC6586409.
- Mackin DM, Perlman G, Davila J, Kotov R, Klein DN. Social support buffers the effect of interpersonal life stress on suicidal ideation and self-injury during adolescence. Psychol Med. 2017 Apr;47(6):1149-1161. doi: 10.1017/S0033291716003275. PMID: 27995812.