We use science to inform the development, evaluation, and implementation of digital tools for behavioral health.


Research Studies
State of the art technologies and interventions, rigorous evaluation of interventions, and improvement of research and implementation methodologies.

Program Reviews
Synthesizing current research on digital health technologies for substance use disorders and co-occurring conditions.

Research Tools
The latest resources and best practice guidelines to assist researchers in studying digital health technologies.
About CTBH
CTBH is organized into five cores: Treatment Development & Evaluation, Emerging Technologies & Data Analytics, Dissemination & Implementation, Pilot and Administrative. Core activities focus on identifying and studying state-of-the-art issues related to digital therapeutics for behavioral health.
Recent Center Highlights
- CTBH receives 7-year grant for its Northeast Node of the National Drug Abuse Treatment Clinical Trials Network! Learn More
- CTBH in the News! PCORI funding awarded to test effectiveness of video as a communication tool for ALS patients and their caregivers Learn More
- CTBH in the News! Groundbreaking clinical trial of AI therapy chatbot shows promising results for software-based mental health care Learn More

Eye on Innovation
- Preliminary Effectiveness of Family Therapy for Perinatal Depressive Symptoms: Results From a Pilot Randomized Trial.
Cluxton-Keller F, Xie H, Hegel MT, Donnelly CL, Bruce ML. Preliminary Effectiveness of Family Therapy for Perinatal Depressive Symptoms: Results From a Pilot Randomized T ...
- Agentic AI and the Architecture of Healthcare Transformation
Article Excerpt: Agentic AI refers to intelligent, task-specific systems that can ingest complex data, interpret context, reason across criteria, and collaborate with hum ...
- Digital Interventions for Recreational Cannabis Use Among Young Adults: Systematic Review, Meta-Analysis, and Behavior Change Technique Analysis of Randomized Controlled Studies.
Cote J, Chicoine G, Vinette B, et al. Digital Interventions for Recreational Cannabis Use Among Young Adults: Systematic Review, Meta-Analysis, and Behavior Change Techni ...